Cairo Homes for Sale

Cairo Homes for Sale

Welcome to Cairo, Missouri, a charming small town nestled in Randolph County, where the warmth of community spirit meets the allure of tranquil living. With its rich history and picturesque landscapes, Cairo is an ideal destination for those seeking a peaceful retreat while still enjoying the conveniences of modern life.

Cairo boasts a friendly atmosphere, where neighbors know each other and local businesses thrive. The town is surrounded by beautiful natural scenery, perfect for outdoor enthusiasts who enjoy hiking, fishing, and exploring the great outdoors. The area is also known for its vibrant community events, from seasonal festivals to farmers' markets, ensuring there’s always something happening to bring residents together.

As for homes for sale in Cairo, you’ll find a delightful variety of properties that cater to diverse lifestyles and budgets. Whether you’re searching for a cozy starter home, a charming historic property, or a spacious family residence, Cairo has something to offer everyone. Many homes feature classic architecture, large yards, and easy access to local amenities, making them perfect for families, retirees, or anyone looking to enjoy a slower pace of life.

Cairo’s affordable real estate market provides an excellent opportunity for first-time homebuyers and investors alike. With a friendly community, beautiful surroundings, and a variety of homes to choose from, Cairo, MO is not just a place to live; it’s a place to call home. Explore the available listings today and discover the charm of Cairo for yourself!

Newest Cairo Homes for Sale

3 Beds ⋅ 2 Baths ⋅ 436839 MLS

Exceptional 2022-built 3-bedroom, 2-bath home on 5.4 acres, thoughtfully designed for comfort, efficiency, and everyday living. This all-electric home features an HVAC heat-pump system and a 5-foot crawl space with a vapor barrier installed during construction. Warm, tasteful finishes and a charming color palette create an inviting atmosphere throughout. The property also offers two impressive outbuildings. The fully enclosed 36' × 50' shop includes a concrete slab floor, full electrical service for a wide range of equipment, and a large wood-burning furnace for year-round use. A second 36' × 40' building, enclosed on three sides, provides excellent equipment storage along with ample electrical hookups. Well-built property is an exceptional opportunity.

1362 HIGHWAY CC, Cairo

Courtesy of Century 21 McKeown & Associates, Inc.

4 Beds ⋅ 3 Baths ⋅ 436698 MLS

Welcome to this spacious and versatile split-design ranch home with a walk-out basement, offering approximately 3,000 square feet of comfortable living space nestled on 6 beautiful acres. With 4 bedrooms and 3 full bathrooms, this property provides the perfect balance of functionality and room to grow, both inside and out. The main living area features a cozy carpeted living room with ample space for relaxing or entertaining, complete with a built-in bookshelf and additional storage. The kitchen is designed with practicality in mind, offering abundant cabinet and counter space, a convenient bar seating area, and a dining space large enough for gatherings, all enhanced by built-in shelving and views overlooking the back patio.

1790 COUNTY ROAD 1815, Cairo

Courtesy of Century 21 Community

2 Beds ⋅ 2 Baths ⋅ 26-406 MLS

Great location for this charming 2-bedroom, 2-bath shop house just outside Cairo, MO. Eye-catching interior finishes include open shelving in kitchen and bathrooms, a live-edge mantel, and cable railing on the stairs. All appliances, including the washer and dryer, convey with the property. The shop features its own mini-split system, 16-foot ceilings, and a 14-foot overhead door, providing plenty of space for projects, storage, or equipment. The home is heated and cooled by multiple mini-split units. The spacious lot offers excellent flexibility, with room to build a second home while keeping the existing property as a shop, or expand the current shop house for an even larger footprint. A unique property with plenty of possibilities!

2164 County Road 1390, Cairo

Courtesy of Weichert, Realtors-House of Brokers 573-256-8601

2 Beds ⋅ 2 Baths ⋅ 436658 MLS

Great location for this charming 2-bedroom, 2-bath shop house just outside Cairo, MO. Eye-catching interior finishes include open shelving in kitchen and bathrooms, a live-edge mantel, and cable railing on the stairs. All appliances, including the washer and dryer, convey with the property. The shop features its own mini-split system, 16-foot ceilings, and a 14-foot overhead door, providing plenty of space for projects, storage, or equipment. The home is heated and cooled by multiple mini-split units. The spacious lot offers excellent flexibility, with room to build a second home while keeping the existing property as a shop, or expand the current shop house for an even larger footprint. A unique property with plenty of possibilities!

2164 COUNTY ROAD 1390, Cairo

Courtesy of Weichert, Realtors - House of Brokers

3 Beds ⋅ 2 Baths ⋅ 10073495 MLS

Enjoy the charm of a small community with the space you've been looking for. Situated on nearly an acre in Cairo, this well maintained 3-bedroom, 2-bath home offers a comfortable layout and modern living with that country feeling. Valuable updates throughout the home include a newer roof and water heater, LVP flooring, and a composite deck. There is an eat in kitchen space, as well as a formal dining room, perfect for any host. Your primary suite features his and hers closets and a heat lamp in your master bath. The detached 2 car garage provides plenty of room for a shop, hobbies, or storage. The spacious lot has endless possibilities to enjoy the outdoors. A property that combines small-town living with room to grow! Go Bearcats!

105 Baker Street, Cairo

Courtesy of Weichert, Realtors - House of Brokers

3 Beds ⋅ 2 Baths ⋅ 132421 MLS

Enjoy the charm of a small community with the space you've been looking for. Situated on nearly an acre in Cairo, this well maintained 3-bedroom, 2-bath home offers a comfortable layout and modern living with that country feeling. Valuable updates throughout the home include a newer roof and water heater, LVP flooring, and a composite deck. There is an eat in kitchen space, as well as a formal dining room, perfect for any host. Your primary suite features his and hers closets and a heat lamp in your master bath. The detached 2 car garage provides plenty of room for a shop, hobbies, or storage. The spacious lot has endless possibilities to enjoy the outdoors. A property that combines small-town living with room to grow.

105 Baker St, Cairo

Courtesy of WEICHERT,REALTORS-HOUSE OF BROKERS 573-446-6767

3 Beds ⋅ 1 Baths ⋅ 26-267 MLS

Enjoy lake life in this move-in ready 3-bedroom, 1-bath home on the big lake at Holiday Acres near Cairo, MO, between Moberly and Macon. Recent updates include a metal roof, flooring, mini-split units, and a dock built in 2022. Relax on the multi-level front deck overlooking the lake or gather around the waterside firepit. The dock features lifts for a boat, jet skis, and kayaks, plus ample seating space. Home furnishings, outdoor furniture, boat, and jet skis are negotiable.

425 W Shore Dr, Cairo

Courtesy of Weichert, Realtors-House of Brokers 573-256-8601

4 Beds ⋅ 2 Baths ⋅ 434958 MLS

Welcome to Briarwood Estates in Cairo! Situated on approximately 5 scenic acres just outside of town, this beautiful 4-bedroom, 2-bath home offers the perfect mix of modern style and comfortable living. Built in 2017, the home features an open-concept layout with contemporary finishes and a warm, inviting feel throughout. All living space is conveniently located on one level, offering both comfort and functionality. Spacious living and kitchen areas are perfect for entertaining, while the generously sized bedrooms provide plenty of room for family and guests. Enjoy peaceful country living with the convenience of being just minutes from town. An oversized attached 2-car garage offers extra storage and workspace. Don't miss this opportunity for modern living with room to roam!

1987 COUNTY ROAD 1620, Cairo

Courtesy of Weichert, Realtors - House of Brokers

3 Beds ⋅ 1 Baths ⋅ 434765 MLS

Enjoy lake life in this move-in ready 3-bedroom, 1-bath home on the big lake at Holiday Acres near Cairo, MO, between Moberly and Macon. Recent updates include a metal roof, flooring, mini-split units, and a dock built in 2022. Relax on the multi-level front deck overlooking the lake or gather around the waterside firepit. The dock features lifts for a boat, jet skis, and kayaks, plus ample seating space. Home furnishings, outdoor furniture, boat, and jet skis are negotiable.

425 W SHORE DR, Cairo

Courtesy of Weichert, Realtors - House of Brokers

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Listing information is provided courtesy of the Broker Reciprocity/IDX of Bagnell Dam Association of REALTORS® and Lake of the Ozarks Board of REALTORS®, Inc. Multiple Listing Services. Copyright 2026 Multiple Listing Service, Inc. of Bagnell Dam Association of REALTORS® MLS, Inc. and Lake of the Ozarks Board of REALTORS® MLS, Inc. Information is being provided for consumers’ personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Information herein is believed to be accurate and timely, but no warranty as such is expressed or implied. 2026 Century 21 Community