Cairo Homes for Sale

Welcome to Cairo, Missouri, a charming small town nestled in Randolph County, where the warmth of community spirit meets the allure of tranquil living. With its rich history and picturesque landscapes, Cairo is an ideal destination for those seeking a peaceful retreat while still enjoying the conveniences of modern life.

Cairo boasts a friendly atmosphere, where neighbors know each other and local businesses thrive. The town is surrounded by beautiful natural scenery, perfect for outdoor enthusiasts who enjoy hiking, fishing, and exploring the great outdoors. The area is also known for its vibrant community events, from seasonal festivals to farmers' markets, ensuring there’s always something happening to bring residents together.

As for homes for sale in Cairo, you’ll find a delightful variety of properties that cater to diverse lifestyles and budgets. Whether you’re searching for a cozy starter home, a charming historic property, or a spacious family residence, Cairo has something to offer everyone. Many homes feature classic architecture, large yards, and easy access to local amenities, making them perfect for families, retirees, or anyone looking to enjoy a slower pace of life.

Cairo’s affordable real estate market provides an excellent opportunity for first-time homebuyers and investors alike. With a friendly community, beautiful surroundings, and a variety of homes to choose from, Cairo, MO is not just a place to live; it’s a place to call home. Explore the available listings today and discover the charm of Cairo for yourself!

Newest Cairo Homes for Sale

$329,000

3 Beds ⋅ 2 Baths ⋅ 26-376 MLS

Just minutes from Cairo, this beautiful 3-bedroom, 2-bath home offers the perfect blend of comfort, style, and outdoor fun. Inside, you'll find 9-foot ceilings throughout with a vaulted ceiling in the spacious living room, along with eye-catching feature walls in the entryway and dining room that add warmth and character. The kitchen is designed for both function and style with custom soft-close maple cabinetry, granite countertops, with all appliances included--even the washer and dryer. The energy-efficient electric heat pump is just two years old, and the attached 2-car garage is equipped with its own mini-split system and provides abundant lighted attic storage above. Outside, enjoy a large back patio overlooking the yard, complete with mature fruit trees and a zip line that's sure to be a hit with family and guests alike. This move-in-ready home offers the peaceful setting you've been looking for, just minutes Highway 63.

2398 County Road 1390, Cairo

Courtesy of Weichert, Realtors-House of Brokers 573-256-8601

$329,000

3 Beds ⋅ 2 Baths ⋅ 436288 MLS

Just minutes from Cairo, this 3-bedroom, 2-bath home offers 9-foot ceilings throughout, a vaulted living room, and feature walls in the entry and dining room. The kitchen features custom soft-close maple cabinets, granite countertops, and all appliances convey, including the washer and dryer. The electric heat pump is just 2 years old. The attached 2-car garage features a mini-split plus abundant lighted attic storage above. Step outside to enjoy the large back patio, mature fruit trees, and a zip line. Move-in ready with thoughtful updates and plenty of room to enjoy both indoors and out.

2398 COUNTY ROAD 1390, Cairo

Courtesy of Weichert, Realtors - House of Brokers

$295,000

3 Beds ⋅ 2 Baths ⋅ 132469 MLS

Welcome home to this charming 3bedroom, 2bath, over 2300 sqft one level home sitting on nearly half an acre right here in Cairo! From the moment you walk into the foyer/Dining Room, you'll feel that comfortable small-town charm. You'll notice the hardwood floors, the sweet sitting bench under the window, and tucked right inside that bench is a storm shelter: neat, right? The living room is massive with taller ceilings, and there is even a bonus room off the side of the living room that would be perfect for an office, hobby room, extra storage, or whatever your family needs! The kitchen is cute as can be with tiled flooring, all kitchen appliances included, and that cozy ''home-cooked meal'' feel. The large primary suite gives you plenty of space to unwind, featuring a full bathroom with a 60-inch vanity, tub/shower combo, skylight for natural light, and a walk-in closet. The other two bedrooms are nice-sized too! One of the sweetest spots in the whole home is the four-season sunroom with tall ceilings and a private hot tub. Outside, you'll find a spacious 30x60 shop with concrete flooring, electric, water plus a couple of overhead doors. It just needs someone to bring it back to life! It even had living quarters at one time, so the possibilities are definitely there again. Lots of extras in this home, including a crawl space (something you do not find often in town) an attic fan, a whole-house humidifier, a newer roof, and a newer furnace! Sitting on 0.49 acres in good ol' Bearcat Country, this property offers a solid all-brick home, a great shop, and a whole lot of potential!

418 W Martin St, Cairo

Courtesy of WEICHERT,REALTORS-HOUSE OF BROKERS 573-446-6767

$295,000

3 Beds ⋅ 2 Baths ⋅ 10073654 MLS

Welcome home to this charming 3bedroom, 2bath, over 2300 sqft one level home sitting on nearly half an acre right here in Cairo! From the moment you walk into the foyer/Dining Room, you'll feel that comfortable small-town charm. You'll notice the hardwood floors, the sweet sitting bench under the window, and tucked right inside that bench is a storm shelter: neat, right? The living room is massive with taller ceilings, and there is even a bonus room off the side of the living room that would be perfect for an office, hobby room, extra storage, or whatever your family needs! The kitchen is cute as can be with tiled flooring, all kitchen appliances included, and that cozy ''home-cooked meal'' feel. The large primary suite gives you plenty of space to unwind, featuring a full bathroom with a tub/shower, skylight for natural light, and a walk-in closet. The other two bedrooms are nice-sized too! One of the sweetest spots in the whole home is the four-season sunroom with tall ceilings and a private hot tub. Outside, you'll find a spacious 30x60 shop with concrete flooring, electric, water plus a couple of overhead doors. It just needs someone to bring it back to life! It even had living quarters at one time, so the possibilities are definitely there again. Lots of extras in this home, including a crawl space (something you do not find often in town) an attic fan, a whole-house humidifier, a newer roof, and a newer furnace! Sitting on 0.49 acres in good ol' Bearcat Country, this property offers a solid all-brick home, a great shop, and a whole lot of potential!

418 W Martin Street, Cairo

Courtesy of Weichert, Realtors - House of Brokers

$295,000

3 Beds ⋅ 2 Baths ⋅ 26-354 MLS

418 W Martin St, Cairo

Courtesy of Weichert, Realtors-House of Brokers 573-256-8601

$295,000

3 Beds ⋅ 2 Baths ⋅ 436002 MLS

Charming 3bedroom, 2bath, over 2300 sqft one level home sitting on nearly half an acre right here in Cairo! From the moment you walk into the foyer/Dining Room, you'll feel that comfortable small-town charm. You'll notice the hardwood floors, the sweet sitting bench under the window, and tucked right inside that bench is a storm shelter: neat, right? The living room is massive with taller ceilings, and there is even a bonus room off the side of the living room that would be perfect for an office, hobby room, extra storage, or whatever your family needs! The kitchen is cute as can be with tiled flooring, all kitchen appliances included, and that cozy ''home-cooked meal'' feel. The large primary suite gives you plenty of space to unwind, featuring a full bathroom with a tub/shower, skylight for natural light, and a walk-in closet. The other two bedrooms are nice-sized too! One of the sweetest spots in the whole home is the four-season sunroom with tall ceilings and a private hot tub. Outside, you'll find a spacious 30x60 shop with concrete flooring, electric, water plus a couple of overhead doors. It just needs someone to bring it back to life! It even had living quarters at one time, so the possibilities are definitely there again. Lots of extras in this home, including a crawl space (something you do not find often in town) an attic fan, a whole-house humidifier, a newer roof, and a newer furnace! Sitting on 0.49 acres in good ol' Bearcat Country, this property offers a solid all-brick home, a great shop, and a whole lot of potential!

418 W MARTIN ST, Cairo

Courtesy of Weichert, Realtors - House of Brokers

$320,000

3 Beds ⋅ 1 Baths ⋅ 26-267 MLS

Enjoy lake life in this move-in ready 3-bedroom, 1-bath home on the big lake at Holiday Acres near Cairo, MO, between Moberly and Macon. Sellers will include the pontoon boat with an accepted contract executed by August 31, 2026, that closes within 60 days--a $10,000 value at no additional cost. Recent updates include a metal roof, flooring, mini-split units, and a dock built in 2022. Relax on the multi-level front deck overlooking the lake or gather around the waterside firepit. The dock features lifts for a boat, jet skis, and kayaks, plus ample seating space. Home furnishings, outdoor furniture, and jet skis are negotiable.

425 W Shore Dr, Cairo

Courtesy of Weichert, Realtors-House of Brokers 573-256-8601

$353,900

4 Beds ⋅ 2 Baths ⋅ 434958 MLS

Welcome to Briarwood Estates in Cairo! Situated on approximately 5 scenic acres just outside of town, this beautiful 4-bedroom, 2-bath home offers the perfect mix of modern style and comfortable living. Built in 2017, the home features an open-concept layout with contemporary finishes and a warm, inviting feel throughout. All living space is conveniently located on one level, offering both comfort and functionality. Spacious living and kitchen areas are perfect for entertaining, while the generously sized bedrooms provide plenty of room for family and guests. Enjoy peaceful country living with the convenience of being just minutes from town. An oversized attached 2-car garage offers extra storage and workspace. Don't miss this opportunity for modern living with room to roam!

1987 COUNTY ROAD 1620, Cairo

Courtesy of Weichert, Realtors - House of Brokers

$320,000

3 Beds ⋅ 1 Baths ⋅ 434765 MLS

425 W SHORE DR, Cairo

Courtesy of Weichert, Realtors - House of Brokers

Start Your Search

Listing information is provided courtesy of the Broker Reciprocity/IDX of Bagnell Dam Association of REALTORS® and Lake of the Ozarks Board of REALTORS®, Inc. Multiple Listing Services. Copyright 2026 Multiple Listing Service, Inc. of Bagnell Dam Association of REALTORS® MLS, Inc. and Lake of the Ozarks Board of REALTORS® MLS, Inc. Information is being provided for consumers’ personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Information herein is believed to be accurate and timely, but no warranty as such is expressed or implied. 2026 Century 21 Community